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HomeminewsReasons for Transplant Failure Rate

Reasons for Transplant Failure Rate

U.S. researchers have found that corneal transplant failure rate was about four times higher in patients diagnosed with corneal oedema (swelling) associated with either intraocular lens (IOL) implants or no natural lens following cataract removal, than in patients diagnosed with Fuchs’ dystrophy, a disorder of the corneal endothelial layer.

In the study published in the June issue of Ophthalmology, the 27 per cent of patients diagnosed with IOL-associated corneal oedema whose transplants failed may have shared an underlying problem: an abnormal reaction to cataract surgery and/or IOLs that negatively impacted the cornea in some way.

In contrast, Fuchs’ dystrophy patients had only a 7 per cent failure rate, including those who had IOLs. The failure rate for participants who did not have glaucoma was 11 per cent versus failure rates of 20 per cent, 29 per cent and 58 per cent for glaucoma patients treated with medications alone, surgery alone, or both, respectively.